Two-compartment model of inner medullary vasculature supports dual modes of vasopressin-regulated inner medullary blood flow
نویسندگان
چکیده
منابع مشابه
Two-compartment model of inner medullary vasculature supports dual modes of vasopressin-regulated inner medullary blood flow.
The outer zone of the renal inner medulla (IM) is spatially partitioned into two distinct interstitial compartments in the transverse dimension. In one compartment (the intercluster region), collecting ducts (CDs) are absent and vascular bundles are present. Ascending vasa recta (AVR) that lie within and ascend through the intercluster region (intercluster AVR are designated AVR(2)) participate...
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We use a mathematical model to explore the possibility that metabolic production of net osmoles in the renal inner medulla (IM) may participate in the urine concentrating mechanism. Anaerobic glycolysis (AG) is an important source of energy for cells of the IM, since this region of the kidney is hypoxic. AG is also a source of net osmoles, since it splits each glucose into two lactate molecules...
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We used a mathematical model to explore the possibility that metabolic production of net osmoles in the renal inner medulla (IM) may participate in the urine-concentrating mechanism. Anaerobic glycolysis (AG) is an important source of energy for cells of the IM, because this region of the kidney is hypoxic. AG is also a source of net osmoles, because it splits each glucose into two lactate mole...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2010
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00072.2010